Use of automated insulin delivery systems in people with type  1 diabetes fasting during Ramadan: An observational study

In well-managed people with type  1 diabetes, Ramadan fasting while using commercial and open-source automated insulin delivery systems can be achieved with no compromise on safety and efficacy when compared with time outside Ramadan (Time in range before Ramadan-blue, during Ramadan-green and after Ramadan-purple). AbstractFasting among people with type  1 diabetes imposes the risk of metabolic decompensation. Automated insulin dosing systems can allow better glycemic control without safety concerns. The utility in prolonged and repetitive fasting has not been studied. In this observational study, validated glycemic data were reviewed and analyze d from people with type 1 diabetes who observed fasting during Ramadan in 2019 and 2020 using automated insulin dosing systems. Six profiles met the inclusion criteria. The average age was 33.7 ± 4.8 years, diabetes duration was 23.5 ± 7.9 years, body mass index 23.6 ± 1.9 kg/ m2 and glycated hemoglobin was 6.3  ± 0.2% (45 ± 5 mmol/mol). The average glucose during Ramadan was 7.0 ± 0.5 mmol/L (126 ± 9 mg/dL), coefficient of variation 28.5%, percentage of time in range 3.9–10 mmol/L (70–180 mg/dL) 88.8 ± 7.3% and percentage time<3.9  mmol/L (<70.0  mg/dL) 2.5 ± 1.3%. The number of fasting days was 27.3 ± 3.3, and the number of days where fasting was broken due diabetes was 1 ± 1.5/participant. No significant differences in glycemic outcomes wer...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Short Report Source Type: research