Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)

CONCLUSIONS: We suggest that the tumorigenic potential conferred by the D631Y mutation is lower than that conferred by the C634R/W mutation, but higher than that conferred by C630Y. Thus, the risk level of the RET D631Y variant appears to be higher than that of C630Y and lower than that of C634R/W.PMID:34905813 | DOI:10.3904/kjim.2021.311
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Source Type: research