Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma
Conclusion
PlGF blockade leads to a reduction in intratumorous hypoxia and metastatic dissemination, enhanced chemotherapy sensitivity and increased survival in mice-bearing aggressive ICC.
Source: Gut - Category: Gastroenterology Authors: Aoki, S., Inoue, K., Klein, S., Halvorsen, S., Chen, J., Matsui, A., Nikmaneshi, M. R., Kitahara, S., Hato, T., Chen, X., Kawakubo, K., Nia, H. T., Chen, I., Schanne, D. H., Mamessier, E., Shigeta, K., Kikuchi, H., Ramjiawan, R. R., Schmidt, T. C., Iwasak Tags: Open access, Gut Hepatology Source Type: research
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