Increased gene expression of B cell ‐activating factor of tumor necrosis factor family, in remitting antineutrophil cytoplasmic antibody‐associated vasculitis patients
ConclusionBAFF gene is significantly expressed in patients with AAV. Among AAV patients, there is a significantly higher expression of BAFF and APRIL in remitting state of the disease as compared to active state. There is no significant change in APRIL gene expression in patients with AAV as compared to controls. This makes a case for anti-BAFF therapy in future for AAV patients in northern India.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Saket Jha,
Jagdeep Singh,
Ranjana W. Minz,
Aadhar Dhooria,
GSRSNK Naidu,
Rajiv Ranjan Kumar,
Manish Rathi,
Sanjay Jain,
Shashi Anand,
Aman Sharma Tags: ORIGINAL ARTICLE Source Type: research