Ocular Flutter in Acute Doxylamine Intoxication

Doxylamine is a widely available first-generation antihistamine used as a sleep aid. Some first-generation antihistamines, such as doxylamine and diphenhydramine, may block voltage-gated sodium channels. Doxylamine toxicity could include ocular flutter in addition to an antihistaminic/antimuscarinic syndrome, causing encephalopathy and mydriasis.

http://cp.neurology.org/cgi/content/short/11/5/e740?rss=1

Source: Neurology Clinical Practice - October 11, 2021 Category: Neurology Authors: Li, D. Z., Williams, Z. R., Nacca, N., Lizarraga, K. J. Tags: Clinical neurology examination, Ocular motility Case Source Type: research