Long-term Safety and Efficacy of Mexiletine in Myotonic Dystrophy Types 1 and 2

Conclusions These findings support that mexiletine is both safe and effective when used long-term in myotonic dystrophy. Classification of Evidence This study provides Class IV evidence that mexiletine is a well-tolerated and effective treatment for myotonic dystrophy types 1 and 2.

http://cp.neurology.org/cgi/content/short/11/5/e682?rss=1

Source: Neurology Clinical Practice - October 11, 2021 Category: Neurology Authors: Mousele, C., Matthews, E., Pitceathly, R. D. S., Hanna, M. G., MacDonald, S., Savvatis, K., Carr, A., Turner, C. Tags: All Health Services Research, All Clinical Neurology, All Neuromuscular Disease, Class IV, Cohort studies Source Type: research