Preventing Cardiomyopathy in DMD: A Randomized Placebo-Controlled Drug Trial

Conclusions Combination therapy was well tolerated. Consistent with the previous prophylactic perindopril heart study, there was no evidence of group benefit after 36-month treatment. Classification of Evidence This study provides Class I evidence that combination perindopril-bisoprolol therapy was well tolerated but did not change decline in LVEF significantly in boys with DMD.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: Muscle disease, Clinical trials Randomized controlled (CONSORT agreement), All Pediatric, Cardiac; see Cerebrovascular Disease/Cardiac Research Source Type: research