Prenatal exposure to mixtures of persistent environmental chemicals and fetal growth outcomes in Western Australia

CONCLUSIONS: Using a Bayesian penalized regression method, we assessed the shapes of exposure-response relationships, controlled for confounding by co-exposure, and estimated the single and combined effects of a large mixture of correlated environmental chemicals on fetal growth. Our findings, based on a small sample of mother-neonate pairs, suggest that mixtures of persistent chemicals are not associated with birth weight, length, and head circumference. The potential for non-monotonic relationships between environmental chemicals and fetal growth outcomes warrants further study.PMID:34883336 | DOI:10.1016/j.ijheh.2021.113899
Source: International Journal of Hygiene and Environmental health - Category: Environmental Health Authors: Source Type: research