Central nervous system involvement of anaplasmosis

BMJ Case Rep. 2021 Dec 8;14(12):e243665. doi: 10.1136/bcr-2021-243665.ABSTRACTA 64-year-old woman presented with 24 hours of lethargy, confusion, headache, nausea and vomiting. Examination revealed expressive aphasia, conjunctival suffusion and a tick embedded in her popliteal fossa. Labs revealed hyponatraemia, transaminitis, leucopenia, thrombocytopenia and an elevated C reactive protein. Peripheral blood smear was unremarkable. MRI/magnetic resonance angiogram revealed bilateral frontoparietal subarachnoid haemorrhage which was further confirmed by lumbar puncture which revealed six nucleated cells, 92% lymphocytes, 1460 red blood cells, normal glucose and protein and negative cryptococcal antigen, herpes simplex PCR and Lyme PCR. Serum Lyme IgG/IgM antibodies and PCR, Erlichia chaffeensis serum IgG/IgM antibodies and PCR and anaplasma serum IgG/IgM antibodies were negative. Anaplasmosis serum PCR was positive. The tick was identified as Ixodes scapularis The patient was diagnosed with anaplasmosis and treated with 21 days of doxycycline resulting in improvement of symptoms, but lingering headaches and word finding difficulties.PMID:34880034 | DOI:10.1136/bcr-2021-243665
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research

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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Vaccines and immunisation Coronavirus Health Infectious diseases Science US news World news Source Type: news
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Thread Starter Can you get a job whilst studying medicine? Follow 1 hour ago 1 hour ago Quote: Originally Posted by jessicanaude Okay, thank you! Lectures etc are timetabled pretty much 9-5 every day. Some work at weekend but it’s hard to juggle your workload
Source: The Student Room - Category: Universities & Medical Training Authors: Tags: Medicine Source Type: forums
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Source: Translational Stroke Research - Category: Neurology Source Type: research
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This study was registered at chictr.org.cn as # ChiCTR2100050646.PMID:35040375 | DOI:10.1080/09537104.2022.2026910
Source: Platelets - Category: Hematology Authors: Source Type: research
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Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
More News: Anaplasmosis | Angiography | Aphasia | Cold Sores | Doxycycline | Headache | Herpes | Infectious Diseases | Lumbar Puncture | Lyme Disease | Migraine | Papanicolaou (Pap) Smear | Subarachnoid Hemorrhage | Thrombocytopenia