Clinical and Histopathological Features of Scleroderma-like Disorders: An Update

Medicina (Kaunas). 2021 Nov 20;57(11):1275. doi: 10.3390/medicina57111275.ABSTRACTScleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical-pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud's phenomenon and capillaroscopic anomalies constitutes an important element of differential diagnosis with systemic sclerosis. When scleroderma can be excluded, on the basis of the main body sites, clinical evolution, any associated pathological conditions and specific histological features, it is possible to make a correct diagnosis.PMID:34833493 | PMC:PMC8625286 | DOI:10.3390/medicina57111275

Source: Medicina (Kaunas) - November 27, 2021 Category: Universities & Medical Training Authors: Rosario Foti Rocco De Pasquale Ylenia Dal Bosco Elisa Visalli Giorgio Amato Pietro Gangemi Riccardo Foti Alice Ramondetta Source Type: research