Body Region-Specific 3D Age-Scaling Functions for Scaling Whole-Body Computed Tomography Anatomy for Pediatric Late Effects Studies

Conclusion:We have successfully evaluated our ASFs by scaling UF/NCI computational phantoms from one age to another age, which demonstrates the feasibility of scaling any CT-based anatomy. We have found that dose to organs of exact age-scaled and nearest aged-matched phantoms are significantly different (p<0.05) which indicates that using the exact age-scaled phantoms for retrospective dosimetric studies is a bette.PMID:34874300 | DOI:10.1088/2057-1976/ac3f4e

Source: Cancer Control - December 7, 2021 Category: Cancer & Oncology Authors: Aashish Chandra Gupta Constance A Owens Suman Shrestha Choonsik Lee Susan A Smith Rita E Weathers Tucker Netherton Peter A Balter Stephen F Kry David S Followill Keith Tchadwick Griffin James P Long Gregory T Armstrong Rebecca M Howell Source Type: research