Observations on improving Covid-19 vaccination responses in Kidney Transplant Recipients: heterologous vaccination and immunosuppression modulation

Solid organ transplant recipients have a weaker humoral response to Covid-19 vaccination due to several factors, including lymphopenia associated with immunosuppressive therapies (particularly Belatacept, antiproliferative drugs and steroids)1. Due to the high probability of severe Covid-19 symptoms in this at-risk population2, a third vaccine dose has been proposed for immunocompromised patients by the French National Authority for Health in order to improve humoral responses and vaccine efficiency3.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: letters to the editor Source Type: research