Investigator-Driven Randomised Controlled Trial of Cefiderocol versus Standard Therapy for Healthcare-Associated and Hospital-Acquired Gram-negative Bloodstream Infection: Study protocol (the GAME CHANGER trial): study protocol for an open-label, randomised controlled trial

Increasing rates of antibiotic resistance in Gram-negative organisms due to the presence of extended-spectrum beta-lactamases (ESBL), hyperproduction of AmpC enzymes, carbapenemases and other mechanisms of res...

Source: Trials - December 7, 2021 Category: General Medicine Authors: Hugh Wright, Patrick N. A. Harris, Mark D. Chatfield, David Lye, Andrew Henderson, Tiffany Harris-Brown, Anna Donaldson and David L. Paterson Tags: Study protocol Source Type: research