Impact of 18F-Fluorodeoxyglucose positron emission tomography on management of cancer of unknown primary: systematic review and meta-analysis

Cancers of unknown primary (CUP) have traditionally been treated empirically, with a dismal prognosis. Compared with standard diagnostic tests, including CT and MRI, imaging with 18F-fluorodeoxyglucose (FDG) PET or PET/CT has shown the capacity to better identify the primary tumour site and detect additional sites of metastasis. However, its clinical impact is not well established. We performed a systematic review and meta-analysis of prior studies to assess the impact of FDG-PET or PET/CT on the management of patients with CUP.

Source: European Journal of Cancer - November 2, 2021 Category: Cancer & Oncology Authors: Sungmin Woo, Anton S. Becker, Richard K.G. Do, Heiko Sch öder, Hedvig Hricak, H. Alberto Vargas Tags: Original Research Source Type: research