Viagra could be used to treat Alzheimer ’s disease, study finds

US scientists say users of sildenafil – the generic name for Viagra – are 69% less likely to develop the form of dementia than non-usersViagra could be a useful treatment against Alzheimer ’s disease, according to a US study.Alzheimer ’s disease, the most common form of age-related dementia, affects hundreds of millions of people worldwide. Despite mounting numbers of cases, however, there is currently no effective treatment.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Alzheimer's Dementia Viagra Health Medical research Science US news Source Type: news

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Medical research and development in the context of aging has, like all other medicine, been dominated for a long time by a model in which a single disease is identified by symptoms and then treated. In the context of infectious disease and inherited conditions, this is a good way to go about the matter of investigation, treatment, and assignment of resources. A patient typically has one disease at a time, and the symptoms are distinct and clearly caused by the disease in question. Indeed, the disease paradigm arose from the modern era's long road towards ever more effective control of infectious disease. The institutions a...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
TUESDAY, Jan. 25, 2022 -- Stability in body mass index (BMI) over time is associated with a better cognitive trajectory in older adults, according to a study published online Jan. 20 in Alzheimer's&Dementia. Michal Schnaider Beeri, Ph.D.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
FINDINGSA UCLA-led cost analysis of the controversial new Alzheimer ’s disease drug aducanumab shows that ancillary care services, such as additional MRIs and neurologist visits to monitorthe potentialbrain swelling and bleeding associated with the medication, account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.With 1.1 to 5.7 million Medicare beneficiaries who have mild dementia or cognitive impairment identified as potentially eligible for the drug, these ancillary services could substantially increase annual Medicare spending, the analysis shows.BACKGROUNDIn June 2021...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
CONCLUSION: Our findings of three NPS subgroups in MCI characterized by affect, hyperactive, or psychotic features are largely consistent with a previous 3-factor model of NPS found in a demented population. The consistency of these findings across studies and samples, coupled with our results on the associated risks of converting to dementia, suggests that the NPS structure is robust, and warrants further consideration in classification models of MCI.PMID:35067420 | DOI:10.1016/j.jagp.2021.12.016
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Authors: Source Type: research
CONCLUSION: TF alleviates dementia by reducing Aβ deposition via the ACER2-mediated sphingolipid signaling pathway.PMID:35069753 | PMC:PMC8357478 | DOI:10.1155/2021/6029237
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Source Type: research
CONCLUSION: Our findings of three NPS subgroups in MCI characterized by affect, hyperactive, or psychotic features are largely consistent with a previous 3-factor model of NPS found in a demented population. The consistency of these findings across studies and samples, coupled with our results on the associated risks of converting to dementia, suggests that the NPS structure is robust, and warrants further consideration in classification models of MCI.PMID:35067420 | DOI:10.1016/j.jagp.2021.12.016
Source: Am J Geriatr Psychia... - Category: Geriatrics Authors: Source Type: research
Neural Plast. 2022 Jan 13;2022:5241449. doi: 10.1155/2022/5241449. eCollection 2022.ABSTRACTAlzheimer's disease (AD) is the most common type of dementia but lacks effective treatment at present. Gastrodin (GAS) is a phenolic glycoside extracted from the traditional Chinese herb-Gastrodia elata-and has been reported as a potential therapeutic agent for AD. However, its efficiency is reduced for AD patients due to its limited BBB permeability. Studies have demonstrated the feasibility of opening the blood-brain barrier (BBB) via focused ultrasound (FUS) to overcome the obstacles preventing medicines from blood flow into the ...
Source: Neural Plasticity - Category: Neurology Authors: Source Type: research
Older adults who had cataract removal to restore their vision had a lower risk of Alzheimer ’s disease and other forms of dementia.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Cataracts Alzheimer ' s Disease Eyes and Eyesight Surgery and Surgeons Dementia Brain Glaucoma JAMA Internal Medicine (Journal) Source Type: news
Pain is a significant concern among older adults with Alzheimer's disease and related dementias (ADRD).
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
DEMENTIA is a destructive set of symptoms associated with progressive brain decline. According to research, an "afternoon snack" can increase your risk of Alzheimer's disease - the most common cause of dementia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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