Asymptomatic and pre-symptomatic transmission of sars-cov-2 in a community congregant setting

Conditions:   COVID-19;   SARS-CoV2 Infection Intervention:   Device: Polyvinylalcohol strip [diagnostic] Sponsors:   Colorado School of Public Health;   Colorado State University;   University of Colorado, Boulder;   Colorado Mesa University;   Regis University;   Denver Health Medical Center;   University of Colorado, Colorado Springs;   University of Colorado, Denver Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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When Jeremy Luban first looked over the genetic sequence of the Omicron variant on his phone one day last November, it was five o’clock in the morning. But even at that hour, the University of Massachusetts virus expert knew right away Omicron was a problem. First, there was the sheer number of new mutations—by some counts, as many as 50, with 30 of them in the critical places that vaccines and drug treatments target. Second, this new version of the SARS-CoV-2 virus seemed to appear out of nowhere, unpredictably and with no immediately obvious connection to previous variants. [time-brightcove not-tgx=”tru...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
WEDNESDAY, Jan. 26, 2022 -- For asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR)-positive individuals living with an infected household contact, treatment with the subcutaneous casirivimab and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Authors'conclusions Our review suggests that a broad range of measures implemented in the school setting can have positive impacts on the transmission of SARS ‐CoV‐2, and on healthcare utilisation outcomes related to COVID‐19. The certainty of the evidence for most intervention‐outcome combinations is very low, and the true effects of these measures are likely to be substantially different from those reported here. Measures implemented in the scho ol setting may limit the number or proportion of cases and deaths, and may delay the progression of the pandemic. However, they may also lead to negative unintended conse...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
DNA or RNA-based diagnostic tests for infectious diseases are critical in modern medicine. The current gold standard for COVID-19 detection is testing SARS-CoV-2 viral RNA by quantitative reverse transcription Polymerase Chain Reaction (RT-qPCR). This method involves patient sample collection with a nasopharyngeal swab, storage of the swab in a universal transport medium during transport to testing site, RNA extraction, and analysis of the extracted RNA sample. Collected patient samples – in addition to the possible presence of SARS-CoV-2 – also contain inhibitors for downstream enzymatic reactions, RNA degradi...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Tags: Diagnostics Licensing Desired & Collaboration Desired Collaboration Sought NEI Source Type: research
Org. Biomol. Chem., 2022, Accepted Manuscript DOI: 10.1039/D1OB02125G, Review ArticleGrigory A. Аrtem'ev, Vladimir L. Rusinov, Dmitry S Kopchuk, Maria I. Savchuk, Sougata Santra, Evgeny Ulomsky, Grigory V Zyryanov, Adinath Majee, Weijie Du, Valery Charushin, Oleg N. Chupakhin Fragments of 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-one are found in many compounds with various types of biological activities, including the antiviral drug Riamilovir (Triazavirin ®), which shows an activity against SARS-CoV-2 (COVID-19). Therefore, the development... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Monthly report presenting the latest data on COVID-19 mortality in England in people with laboratory-confirmed SARS-CoV-2. 26 January 2022Added monthly update: report and data. 20 December 2021Added monthly update: report and data.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
In conclusion, the oral LTB-adjuvanted multi-epitope SARS-CoV-2 vaccine triggered versatile humoral, cellular and mucosal immune responses, which are likely to provide protection, while also minimizing technical hurdles presently limiting global vaccination, whether by priming or booster programs.PMID:35078662 | DOI:10.1016/j.vaccine.2022.01.025
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
In this study we assess the potential of a vaccine formulation based on the recombinant RBD domain of SARS-CoV-2 expressed in the thermophilic filamentous fungal strain Thermothelomyces heterothallica and the hepatitis B virus (HBV) core protein. Functional humoral and cellular immune responses were detected in mice. To our knowledge, this is the first report on the immune evaluation of a biomedical product obtained in the fungal strain T. heterothallica. These results together with the intrinsic advantages of this expression platform support its use for the development of biotechnology products for medical purpose.PMID:35...
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
Eur Ann Allergy Clin Immunol. 2022 Jan 26. doi: 10.23822/EurAnnACI.1764-1489.243. Online ahead of print.ABSTRACTAt the beginning of Sars-Cov 2 pandemic, in the absence of "targeted" therapies, the national health authorities have introduced some measures aimed at reducing the spread of infection in the community (lockdown, social distancing, personal protective equipment (PPE), personal hygiene and disinfection of living environments). All the containment measures have led to both positive and negative effects in patients with allergic diseases. We believe that further studies should be undertaken to investigate ...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
We present a record of events that led to the creation of the Puerto Rico Case Investigation and Contact-Tracing System (CICTS) to monitor and control the spread of severe acute respiratory syndrome coronavirus 2 in Puerto Rico. The development of the CICTS is a significant step toward establishing a comprehensive infectious disease surveillance system in Puerto Rico. Furthering the development of a CICTS infrastructure is critical in the response against future emerging infectious diseases in the region. (Am J Public Health. 2022;112(2):223-226. https://doi.org/10.2105/AJPH.2021.306584).PMID:35080940 | DOI:10.2105/AJPH.2021.306584
Source: American Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
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