Predictive risk factors of adverse perinatal outcomes following blunt abdominal trauma in pregnancy - Mehraban SS, Lagodka S, Kydd J, Mehraban S, Cabbad M, Chendrasekhar A, Lakhi NA.

BACKGROUND: The primary objective was to identify predictive risk factors of preterm delivery following blunt abdominal trauma. The secondary objective was to identify risk factors of other adverse outcomes, Neonatal Intensive Care Unit (NICU) admission, p...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

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AbstractPurposeAlthough the gut microbiota (GM) are associated with various diseases, their role in gestational diabetes mellitus (GDM) remains uncharacterized. Further study is urgently needed to expose the real relationship between GM and GDM.MethodsWe performed a prospective study in 33 pregnant Chinese individuals [15, GDM; 18, normal glucose tolerance (NGT)] to observe the fecal microbiota by 16S rRNA gene amplicon sequencing at 24 –28 weeks of gestational age after a standard 75 g oral glucose tolerance test. Linear regression analysis was employed to assess the relationships between the GM and GDM cl...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
ConclusionWell-designed studies are needed to assess verbal and non-verbal neurocognition of offspring born to mothers with autoimmune thyroid disease before or during pregnancy.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Care in Primary Health Care for women in the pregnancy-puerperal cycle must take place in an integral way, with individualized care that considers the life history, feelings and the environment in which the woman lives, seeking her physical and mental well...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Systemic lupus erythematosus flare is distinguished in pregnant women with the highest area under the curve value of 0.990 through the machine learning of metabolic patterns. The patterns are directly extracted through a hollow-Co3O4/C-assisted laser desorption/ionization mass spectrometer using 0.1 µL of serum. This protocol advances real-time diseases monitoring and promises precision diagnosis in clinics. AbstractA noninvasive, easy operation, and accurate diagnostic protocol is highly demanded to assess systemic lupus erythematosus (SLE) activity during pregnancy, promising real-time activity monitoring during th...
Source: Small - Category: Nanotechnology Authors: Tags: Research Article Source Type: research
Environ Res. 2022 Jan 18:112772. doi: 10.1016/j.envres.2022.112772. Online ahead of print.ABSTRACTThe developing perinatal brain is vulnerable to methylmercury (MeHg) exposure. The contribution of breast milk to tissue MeHg levels in offspring is a significant public health concern because breast milk contains a certain amount of MeHg. Here, the contribution of MeHg transferred via breast milk to the Hg levels in the tissues of pups (Wistar rats) was investigated. Mated maternal rats were fed a MeHg (2 ppm)-supplemented or a control diet during pregnancy. Following parturition, male neonates from each group were cross-fost...
Source: Environmental Research - Category: Environmental Health Authors: Source Type: research
DISCUSSION: The early pregnancy period is a potential critical window during which PM10 exposure can influence cord blood DNA methylation. The results from the TL analysis were consistent with previous findings and merit further exploration in future studies. The study underlines the importance of considering gestational windows outside of the predefined trimesters that may not always overlap with biologically relevant windows of exposure.PMID:35063426 | DOI:10.1016/j.envres.2022.112717
Source: Environmental Research - Category: Environmental Health Authors: Source Type: research
CONCLUSION: High serum netrin-1 levels were significantly associated with the development of EOP. The initial serum netrin-1 level may be useful for determining the risk of developing EOP in women with gestational hypertensive disorder.PMID:35063900 | DOI:10.1016/j.ejogrb.2022.01.010
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Source Type: research
Chemosphere. 2022 Jan 18:133662. doi: 10.1016/j.chemosphere.2022.133662. Online ahead of print.ABSTRACTBACKGROUND: Prenatal exposure to metals has been linked with adverse pregnancy outcomes. Oxidative stress and epigenetic changes are potential mechanisms of action.OBJECTIVES: We aimed to examine the associations of individual and mixtures of metal exposures with oxidative stress and DNA methylation among pregnant women.METHODS: We measured a panel of 16 metals and 3 oxidative stress biomarkers including 8-hydroxydeoxyguanosine (8-OHdG), 4-hydroxy-2-nonenal-mercapturic acid (HNE-MA) and 8-isoprostaglandin F2α (8-iso...
Source: Chemosphere - Category: Chemistry Authors: Source Type: research
Angew Chem Int Ed Engl. 2022 Jan 22. doi: 10.1002/anie.202115907. Online ahead of print.ABSTRACTDesirable biosensing assays need to be sensitive, specific, cost-effective, instrument-free, and versatile. Herein we report a new strategy termed CLIPON (CRISPR and Large DNA assembly Induced Pregnancy strips for signal-ON detection) that can deliver these traits. CLIPON integrates commercial pregnancy test strip (PTS) with four biological elements: the human chorionic gonadotropin (hCG), CRISPR-Cas12a, crRNA and cauliflower-like large-sized DNA assemblies (CLD). CLIPON uses Cas12a/crRNA complex both to recognize a target of in...
Source: Angewandte Chemie - Category: Chemistry Authors: Source Type: research
Chemosphere. 2022 Jan 18:133662. doi: 10.1016/j.chemosphere.2022.133662. Online ahead of print.ABSTRACTBACKGROUND: Prenatal exposure to metals has been linked with adverse pregnancy outcomes. Oxidative stress and epigenetic changes are potential mechanisms of action.OBJECTIVES: We aimed to examine the associations of individual and mixtures of metal exposures with oxidative stress and DNA methylation among pregnant women.METHODS: We measured a panel of 16 metals and 3 oxidative stress biomarkers including 8-hydroxydeoxyguanosine (8-OHdG), 4-hydroxy-2-nonenal-mercapturic acid (HNE-MA) and 8-isoprostaglandin F2α (8-iso...
Source: Chemosphere - Category: Chemistry Authors: Source Type: research
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