Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C  + E) or C + E alone: a prospective, randomized trial

To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT  + C + E) are superior in reducing pain in patients with chronic non...
Source: Journal of Orthopaedic Surgery and Research - Category: Orthopaedics Authors: Tags: Research article Source Type: research

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ConclusionPatients with persistent non-specific LBP seem to experience improvement in pain, disability and quality of life years after seeking treatment. However, it remains unclear what factors might have influenced these improvements, and whether they are treatment-related. Studies varied greatly in design, patient population, and methods of data collection. There is still little insight into the long-term natural course of LBP. Additionally, few studies perform repeated measurements during long-term follow-up or report on patient-centered outcomes other than pain or disability.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
CONCLUSIONS: The personal factors "age" and "sex" impact some ICF limitation/restriction categories in cLBP; appropriately addressing these personal features could further improve phase III rehabilitation outcome.Implications for rehabilitationConsistent with calls to explore the age and sex/gender influence on health and disease, little is known how these factors affect the disablement of individuals with chronic back pain.The factors "age" and "sex" drive differences in some categories within the ICF activity/restriction categories.If age- and gender-specific features in activities...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
AbstractPurposeThe Fremantle back awareness questionnaire (FreBAQ) was recently developed as simple and quick tool to assess back-specific body perception in Low back pain (LBP) patients. The aim of the present study was to translate and cross-culturally adapt the Fremantle back awareness questionnaire (FreBAQ) into a Simplified Chinese version (FreBAQ-C), and evaluate the reliability and validity of the FreBAQ-C in patients with non-specific Chronic Low back pain (CLBP).MethodsThe FreBAQ was translated into Chinese according to established methods. Internal consistency was assessed according to Cronbach ’s alpha. Te...
Source: European Spine Journal - Category: Orthopaedics Source Type: research
Conclusions: The findings suggest that different types of exercise rehabilitation were not significantly different on pain reduction, functional disability, and movement control impairment. It is suggested that the participant ’s preference for an approach should also be considered for encouraging them to adhere to exercise.
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
To identify misbeliefs about the origin and meaning of non-specific chronic low back pain and to examine attitudes towards treatment by primary health care providers.
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Research Source Type: research
Introduction Patients with chronic low back pain radiating to the leg (CLBPr) are sometimes referred to a specialised pain clinic for a precise diagnosis based, for example, on a diagnostic selective nerve root block. Possible interventions are therapeutic selective nerve root block or pulsed radiofrequency. Central pain sensitisation is not directly assessable in humans and therefore the term ‘human assumed central sensitisation’ (HACS) is proposed. The possible existence and degree of sensitisation associated with pain mechanisms assumed present in the human central nervous system, its role in the chronificat...
Source: BMJ Open - Category: General Medicine Authors: Tags: Open access, Anaesthesia Source Type: research
Conclusion: Patients with chronic low back pain have a high prevalence of depressive symptoms in China. Duration of pain, pain severity, family function and pain self-efficacy were predictors of depressive symptoms among chronic low back pain patients in China. Early identification of the associated factors may be helpful for the timely management of depressive symptoms.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
AbstractBackgroundIntervertebral disc degeneration (IDD) is a natural progression of age-related processes. Associated with IDD, degenerative disc disease (DDD) is a pathologic condition implicated as a major cause of chronic lower back pain, which can have a severe impact on the quality of life of patients. As degeneration progression is associated with elevated levels of inflammatory cytokines, enhanced aggrecan and collagen degradation, and changes in the disc cell phenotype. The purpose of this study was to investigate the biological and cytological characteristics of rabbit nucleus pulposus mesenchymal stem cells (NPM...
Source: European Journal of Medical Research - Category: Research Source Type: research
WEDNESDAY, Jan. 12, 2022 -- Therapeutic aquatic exercise leads to greater pain alleviation in patients with chronic low back pain compared with physical therapy, according to a study published online Jan. 7 in JAMA Network Open. Meng-Si Peng, from...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Introduction Chronic lower back pain (CLBP) is a frequent cause of medical consultations worldwide, and it results in decreased quality of life and disability. Current treatments for CLBP are often not effective, and alternatives are urgently needed. Three promising possibilities have emerged: (1) open-label placebo treatment reduces chronic pain, (2) placebo treatment is as efficacious as opioid treatment with a high correlation between patient expectation and treatment outcome, and (3) observing positive effects in another patient can improve functional capacity. We hypothesise that treatment expectations can be positive...
Source: BMJ Open - Category: General Medicine Authors: Tags: Open access, Patient-centred medicine Source Type: research
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