Radiosensitisation of SCCVII tumours and normal tissues in mice by the DNA-dependent protein kinase inhibitor AZD7648

CONCLUSION: AZD7648 is a potent radiation sensitiser of both oxic and anoxic tumour cells, but also markedly radiosensitises stem cells in the small intestine and oral mucosa.PMID:34861268 | DOI:10.1016/j.radonc.2021.11.027

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 3, 2021 Category: Radiology Authors: Cho R Hong Chantal D Buckley Way W Wong Praju V Anekal Benjamin D Dickson Gib Bogle Kevin O Hicks Michael P Hay William R Wilson Source Type: research