Editorial: Lung cancer: continuous progress in diagnosis and treatment

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Source: Current Opinion in Oncology - Category: Cancer & Oncology Tags: LUNG AND MEDIASTINUM: Edited by Robert Pirker and Caicun Zhou Source Type: research

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big dreamer here: if you were starting out as a first year med student, what is the path you’d take to secure a dream job specializing in lung cancer and related environmental research/advocacy at an academic medical center? what about while adding on an MBA and wanting to combine academia with entrepreneurship to find better lung cancer therapies?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students (MD) Source Type: forums
SATURDAY, Jan. 22, 2022 -- Tobacco use is far and away the leading cause of lung cancer, but non-smokers are also at risk, experts say. People who smoke have the highest risk, and smokeless tobacco is also a threat. About 90% of lung cancer cases...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
ChemMedChem. 2022 Jan 21. doi: 10.1002/cmdc.202100727. Online ahead of print.ABSTRACTLung cancer is the leading cause of cancer-related deaths and chemoprevention should be developed. We recently identified dihydromethysticin (DHM) as a promising candidate to prevent NNK-induced lung tumorigenesis. To probe its mechanisms and facilitate its future translation, we investigated the structure-activity relationship of DHM on NNK-induced DNA damage in A/J mice. Twenty DHM analogs were designed and synthesized. Their activity in reducing NNK-induced DNA damage in the target lung tissues was evaluated. The unnatural enantiomer of...
Source: ChemMedChem - Category: Chemistry Authors: Source Type: research
Eur J Med Chem. 2022 Jan 12;230:114118. doi: 10.1016/j.ejmech.2022.114118. Online ahead of print.ABSTRACTMethyltransferase complex, such as METTL3/METTL14/WTP, catalyze N6-methyladenosine (m6A), which is the most abundant mRNA modification in mammals. Besides acting as a m6A methyltransferase, METTL3 also regulates mRNA translation and other biological processes. Studies have identified numerous roles and molecular mechanisms associated with METTL3 in multiple biological processes especially in tumors in recent years. Furthermore, targeting METTL3 as an efficient therapeutic way for the treatment of different kinds of tumo...
Source: European Journal of Medicinal Chemistry - Category: Chemistry Authors: Source Type: research
Chest. 2022 Jan 18:S0012-3692(22)00050-2. doi: 10.1016/j.chest.2021.12.667. Online ahead of print.ABSTRACTBACKGROUND: The long-term risk of cardiovascular outcomes from either stereotactic body radiation (SBRT) or three-dimensional conformal radiation (3DCRT)/intensity modulated radiation (IMRT) to treat early-stage non-small cell lung cancer (NSCLC) is largely unknown. As continued adoption of SBRT accelerates, it is important to delineate unforeseen cardiovascular risks associated with treatment.RESEARCH QUESTION: Does the long-term risk of cardiovascular outcomes for early-stage non-small cell lung cancer (NSCLC) patien...
Source: Chest - Category: Respiratory Medicine Authors: Source Type: research
Source: Lung Cancer - Category: Cancer & Oncology Source Type: research
Source: Lung Cancer - Category: Cancer & Oncology Source Type: research
It is estimated that 235,760 new cases of lung cancer will be diagnosed in 2021 and the majority will be non-small cell lung carcinoma (NSCLC). The most common cause of cancer death among men and women in the United States remains lung cancer. There will be approximately 131,880 deaths due to lung cancer in 2021.[1]
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
Lung cancer remains a major cause of preventable death and early diagnosis is critical to improving survival chances. The chest X-ray (CXR) remains the most common initial investigation, but clinical pathways need to support timely diagnosis through, where necessary, escalation of abnormal findings to ensure priority reporting and early CT scan.
Source: Radiography - Category: Radiology Authors: Source Type: research
Source: International Journal of General Medicine - Category: General Medicine Tags: International Journal of General Medicine Source Type: research
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