Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

Condition:   Pancreatic Cancer Intervention:   Radiation: High Dose Rate Brachytherapy (HDR) Intraoperative Radiation Therapy (IORT) Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Condition:   Pancreatic Cancer Intervention:   Radiation: High Dose Rate Brachytherapy (HDR) Intraoperative Radiation Therapy (IORT) Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: SIRT and chemotherapy appears to be an effective treatment for liver metastases from pancreatic cancer, likely to be of most benefit in selected patients with a resected primary tumour and liver only disease. Significant toxicity was observed and the safety of this approach in patients with metastatic pancreatic cancer will need to be confirmed in subsequent studies. Further study is warranted with SIRT and modern chemotherapies.Trial registrationACTRN12606000015549
Source: BMC Cancer - Category: Cancer & Oncology Authors: Source Type: research
More News: Adenocarcinoma | Brachytherapy | Cancer | Cancer & Oncology | Chemotherapy | Pancreas | Pancreatic Cancer | Radiation Therapy | Research