How to live longer: The most 'powerful' way to protect yourself against ageing

AN AUSTRALIAN study comparing medication and nutrition found that diet has the more profound impact on controlling diabetes, stroke and heart disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Conclusion: Older adults with higher burden of CMVD, driven especially by diabetes, are likely to increase the risk of prevalent and incident MCI and dementia.Gerontology
Source: Gerontology - Category: Geriatrics Source Type: research
MONDAY, Jan. 24, 2022 -- Worrying can take a toll on your psyche, but new research suggests that when middle-aged men fret too much, they face a higher risk for developing diabetes, heart disease or stroke down the road. And this increase in risk...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Exp Ther Med. 2022 Feb;23(2):152. doi: 10.3892/etm.2021.11075. Epub 2021 Dec 17.ABSTRACTLong considered a skin-limited condition, psoriasis is currently defined as a chronic, immune-mediated inflammatory disease, presenting, besides the skin changes, important systemic manifestations, the most common being: psoriatic arthritis, cardiovascular disease, metabolic syndrome, diabetes, inflammatory bowel disease and nonalcoholic steatohepatitis. It is a disease with a strong psycho-emotional and social impact, both through skin changes such as pruritic, scaly erythematous plaques, and through the association of comorbidities th...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols. FOXO3...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study aimed to assess the effects of serum calcium and phosphate levels on incident ischemic heart disease (IHD) in a large-scale community-dwelling Korean cohort. We evaluated 15,259 non-diabetic individuals (median age, 45 years; range, 30-85) without previous IHD or ischemic stroke using the Korean National Health Insurance data. The study population was classified based on the calcium, phosphate, and calcium/phosphate ratios. Using Cox proportional hazards regression models, we estimated hazard ratios (HRs) with 95% confidence intervals (CIs) for IHD over 50 months after baseline enrolment. The age- and sex-adjust...
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
SARS-Cov-2 infection may be complicated by atrial flutter, hypercoagulability, TIA, superinfection, and sepsis. AbstractSARS-CoV-2  may not only manifest as pneumonia (COVID-19) but also in other organs, including the brain (neuro-COVID). One of the cerebral complications of SARS-CoV-2 is ischemic stroke. Transitory ischemic attack (TIA) in a SARS-CoV-2 positive has not been reported. A 78-year-old poly-morbid male (diabetes, hypertension, and coronary heart disease), admitted for COVID-19, developed atrial flutter on hospital day (hd) 2. Anticoagulation with enoxaparin was started. On hd5, he experienced a TIA despit...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
The phrase "you are what you eat" is commonly used in conversations about health and the connection between food and the body. Eating an unhealthy diet can have serious consequences and can increase someone's risk of dying from heart disease, stroke and Type 2 diabetes.In this Mayo Clinic Minute, Dr. Stephen Kopecky, a preventive cardiologist at Mayo Clinic, discusses the relationship between food and disease. Watch: The Mayo Clinic Minute https://youtu.be/aNmXH5WIzb0 Journalists: Broadcast-quality video (1:13) is in…
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
This study used data from the UK Biobank, including 357,433 individuals with no cardiometabolic diseases at baseline (stage I) and 35,034 individuals with 1 cardiometabolic disease at baseline (stage II). Pulmonary function was measured by forced vital capacity (FVC) or forced expiratory volume in 1 second (FEV1). We defined CM as the coexistence of at least two cardiometabolic diseases: type 2 diabetes (T2D), coronary heart disease (CHD), and stroke. Multinomial logistic regression models and Cox proportional hazards models were performed to estimate odds ratios (ORs) or hazard ratios (HRs) and their 95% confidence interv...
Source: Chest - Category: Respiratory Medicine Authors: Source Type: research
AbstractAims/hypothesisWe aimed to compare the performance of risk prediction scores for CVD (i.e., coronary heart disease and stroke), and a broader definition of CVD including atrial fibrillation and heart failure (CVD+), in individuals with type 2 diabetes.MethodsScores were identified through a literature review and were included irrespective of the type of predicted cardiovascular outcome or the inclusion of individuals with type 2 diabetes. Performance was assessed in a contemporary, representative sample of 168,871 UK-based individuals with type 2 diabetes (age  ≥18 years without pre-existing CVD+). M...
Source: Diabetologia - Category: Endocrinology Source Type: research
AbstractStroke is the second leading cause of death after coronary heart disease in developed countries and is the greatest cause of disability and cognitive impairment. Risk factors for cognitive impairment and dementia after stroke are multifactorial including older age, family history, hypertension, arterial fibrillation, diabetes, genetic variants, low educational status, vascular comorbidities, prior transient ischaemic attack or recurrent stroke, depressive illness duration of a stroke, location, volume, intensity, and degree of neuronal degeneration, location and size of infarction after stroke, time interval after ...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
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