High cholesterol: The sign 'on the back of your hand' and tendons - how to lower it

HIGH cholesterol does not tend to cause symptoms, though you can find out if you have it from a blood test. We need some cholesterol to stay healthy, though there are some forms which are considered bad for us.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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STATINS are one of the world's most widely prescribed drugs. Despite its impressive effect on cholesterol levels, there are a number of side effects one needs to be aware of.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
SUPPLEMENTS to help lower your cholesterol have yielded some impressive results. Unfortunately, while some may be keeping your cholesterol levels in check, your blood glucose levels could be dangerously rising too.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A plant that lowers "bad" cholesterol, a risk factor for heart disease.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Cholesterol Source Type: blogs
STATINS help to control cholesterol levels, most likely reducing your risk of a heart attack or stroke - both of which can lead to the end of your life.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
AbstractThe triglyceride glucose (TyG) index and triglyceride/high lipoprotein density cholesterol (TG/HDL-C) are two important risk markers to evaluate the insulin resistance and cardiovascular diseases (CVDs). To assess the association between TG/HDL-C and TyG index and CVDs. The Mashhad stroke and heart association disorder cohort study started in 2010 and has been continued until 2020. During 6-year follow-up of 9704 participants, 235 events including 118 acute coronary syndrome (ACS), 83 chronic coronary syndrome, 27 myocardial infarction, and 27 cardiac death were confirmed. SPSS software (version 21) was used for st...
Source: BioFactors - Category: Biochemistry Authors: Tags: Research Communication Source Type: research
Sustained psychological stress is shown to accelerate the progression of atherosclerosis. The most plausible biological explanations involve the effects of stress on (a) the immune system, resulting in raised inflammatory signaling, and on (b) blood pressure. Raised blood pressure can accelerate atherosclerosis, as well as raise the risk of rupture of atherosclerotic lesions. The relationship between stress and atherosclerosis may well have as much to do with the lifestyle effects of stress and their downstream effects on cardiovascular health over the long term, however. Although the specific biological mechanism...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Acta Pharmacol Sin. 2022 Jan 19. doi: 10.1038/s41401-021-00841-y. Online ahead of print.ABSTRACTThe protein arginine methyltransferase 5 (PRMT5), which is highly expressed in tumour tissues, plays a crucial role in cancer development. However, the mechanism by which PRMT5 promotes cancer growth is poorly understood. Here, we report that PRMT5 contributes to lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours. Mass spectrometric analysis identified PRMT5 lysine 387 as its succinylation site. Moreover, the desuccinylation of PRMT5 K387 enhances...
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Source Type: research
Medicine (Baltimore). 2021 Dec 3;100(48):e27973. doi: 10.1097/MD.0000000000027973.ABSTRACTThe incidence of stroke may be increased in patients with coronary artery disease (CAD). We aimed to investigate the specific risk factors for the development of ischaemic and haemorrhagic stroke in stable CAD patients.Patients with stable CAD were prospectively enrolled for future cardiovascular events in Taiwan. All the patients had received coronary interventions and were stable for least 1 month before enrolment. The incidence of ischaemic stroke was identified and confirmed by telephone and hospital records. Baseline characterist...
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
The objective of this review was to discuss the role on PCSK9 in oxidation, inflammation, and atherosclerosis. This function activates proinflammatory cytokine production and affects oxidative modifications within atherosclerotic lesions, revealing its more significant role in atherosclerosis. Although a variety of evidence demonstrates that PCSK9 plays a role in atherosclerotic inflammation, the direct mechanism of involvement is still unknown, driving a gap in knowledge to such a predominant player in cardiovascular disease. Investigation of proteins structurally related to PCSK9 may interestingly be the link in unveilin...
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Conclusion: Favorable CVH was significantly associated with lower HGF levels in this ethnically diverse cohort. Interventions aimed at promoting and preserving favorable CVH may reduce the risk of endothelial injury as indicated by lower serum HGF levels.PMID:35047572 | PMC:PMC8761906 | DOI:10.3389/fcvm.2021.760281
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
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