Detection of cytogenetic changes and chromosomal aneuploidy with fluorescent in situ hybridization in cytological specimens of oral cancers in Fanconi anemia-Proof of concept

CONCLUSIONS: As proof of concept, FISH was able to detect genetic changes and chromosomal aneuploidy discriminating oral cancer from noncancerous lesions in individuals with FA. This supports its application on oral brush biopsy-based cytology.PMID:34854575 | DOI:10.1002/cre2.519

Source: Cell Research - December 2, 2021 Category: Cytology Authors: Bruno Eduardo Silva de Araujo Eunike Velleuer Ralf Dietrich Natalia Pomjanski Isabela Karoline de Santana Almeida Araujo Martin Schlensog Susanne Irmtraud Wells Josephine Christine Dorsman Martin Schramm Source Type: research