CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis

CONCLUSIONS: CircCRIM1 bond with miR-145-5p to work as competing endogenous RNA (ceRNA) of CRIM1, and circCRIM1 bond with miR-383-5p to improve the expression of ZEB2 in ovarian cancer. CircCRIM1 and CRIM1 promoted the ovarian cancer progression and supplied a novel insight into the researches of ovarian cancer.PMID:34847936 | DOI:10.1186/s12958-021-00857-3

Source: Reproductive Biology - December 1, 2021 Category: Reproduction Medicine Authors: Yuping Du Xin Liu Song Zhang Shuo Chen Xue Guan Qianhui Li Xi Chen Yang Zhao Source Type: research