Exploring Patient Preference Heterogeneity for Pharmacological Treatments for Chronic Pain: A Latent Class Analysis

ConclusionsPreference heterogeneity across respondents indicates a need for a personalized approach to offering treatment options. Symptom improvement, cost, physical dependence and route of administration might be important to different patients.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Intravenous thrombolysis (IV –rtPA) has been suggested as a potential cause of myocardial infarction (MI) after acute ischemic stroke (AIS), with randomized clinical trials showing a higher number of cardiac events within the thrombolysis group. We assessed the prevalence and MI mechanisms after IV–rtPA for AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Gout typically affects the big toe because it is furthest from the heart - uric acid is more likely to turn into crystals at the extremities where body temperature is coolest.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Discussion: To the best of our knowledge, this is the first reported case of Aspergillus endogenous endophthalmitis in an immunocompetent patient secondary to pulmonary changes that occurred from previously treated tuberculosis.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Conclusion] Chiropractic Biophysics technique which includes the cervical extension traction using the pediatric Denneroll orthotic was effective in restoring lordosis in a pediatric patient with cervical kyphosis and chronic headaches presenting with recent neck pains from a traumatic origin. Routine X-ray of the cervical spine is recommended for patients presenting with craniocervical symptoms as spine alignment is often overlooked as pathognomonic for these conditions.PMID:35035083 | PMC:PMC8752283 | DOI:10.1589/jpts.34.71
Source: Physical Therapy - Category: Physiotherapy Authors: Source Type: research
Conclusion] We developed a 31-item Katakori Disability Index with content validity.PMID:35035072 | PMC:PMC8752277 | DOI:10.1589/jpts.34.13
Source: Physical Therapy - Category: Physiotherapy Authors: Source Type: research
Am J Transl Res. 2021 Dec 15;13(12):14195-14202. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the feasibility and clinical efficacy of precise puncture combined with simplified percutaneous vertebroplasty (PVP) for treating osteoporotic vertebral compression fractures (OVCF).METHODS: A total of 82 patients with single-segment osteoporotic vertebral compression fractures (OVCF) treated with PVP from Dec. 2016 to Nov. 2018 were retrospectively analyzed. Among the patients, 45 cases in group A accepted precise puncture combined with simplified PVP, and 37 cases in group B underwent conventional PVP. The operative time, ...
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research
Am J Transl Res. 2021 Dec 15;13(12):14168-14175. eCollection 2021.ABSTRACTOBJECTIVE: This research was designed to probe into the influences of natural shoulder delivery combined with free position delivery on pregnant outcome and genital tract of puerperants.METHODS: Totally 128 puerperants who gave birth in our hospital from May 2018 to November 2019 were selected as the research objects. Among them, 66 in traditional position combined with traditional shoulder delivery were assigned to a conventional group (CG), and 62 in free position combined with natural shoulder delivery were assigned to a research group (RG). Their...
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research
Am J Transl Res. 2021 Dec 15;13(12):14149-14156. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of root canal and basic periodontal therapies on the efficacy and inflammatory response in patients with pulpal-periodontal disease.METHODS: Clinical data of 103 patients with combined periodontal-endodontic lesions were retrospectively analyzed. The patients were divided into a control group (n=50, treated with conventional root canal therapy) and an observation group (n=53, treated with root canal and basic periodontal therapies). The clinical efficacy after treatment, as well as the probing pocket depth (PD), p...
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research
Am J Transl Res. 2021 Dec 15;13(12):14133-14140. eCollection 2021.ABSTRACTOBJECTIVES: To explore the role of continuous infusion of intraoperative dexmedetomidine in chronic pain after thoracotomy via the Toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling pathway.METHODS: Seventy-five patients undergoing thoracotomy were randomized into the control group (CG, n=37) and the observation group (OG, n=38). After induction of anesthesia for 30 min and until the end of surgery, the OG was infused with 0.4 μg/(kg·h) dexmedetomidine, and the CG was infused with the same amount of normal saline.RES...
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research
ConclusionIn Japanese patients with OA and CLBP, we saw a trend of increased risk for AMI in patients using NSAIDs for more than 5  years. Elderly patients had a higher prevalence of diabetes, hypertension, and other CVD which increased the risk of AMI. Although NSAID patches were preferred to oral NSAIDs in elderly patients, risk for AMI was similar between the two modalities. Therefore, we suggest using NSAIDs carefully, esp ecially in elderly patients and those at risk of developing CVD.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
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