Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1

CONCLUSION: Hyperbaric oxygen did not significantly improve the healing outcome of osteoradionecrosis after surgical removal of necrotic bone as compared to standard care (70% vs. 51%). This effect is not statistically significant due to the fact that the study was underpowered and is therefore prone to type II error.PMID:34843843 | DOI:10.1016/j.radonc.2021.11.021

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 29, 2021 Category: Radiology Authors: Lone E Forner Fran çois J Dieleman Richard J Shaw Anastasios Kanatas Chris J Butterworth G öran Kjeller Jan Alsner Jens Overgaard S øren Hillerup Ole Hyldegaard Per Arnell Christian von Buchwald Johannes H A M Kaanders Ludi E Smeele Lena Specht J ørge Source Type: research