Transcriptomic and histological analysis of exposed facial skin areas wrinkled or not and unexposed skin

CONCLUSIONS: Expected histological findings and gene expression differences among areas were observed. Photoaging in menopausal women may modulate lipid and aminoacids metabolism and decrease inflammatory and keratinization pathways, cellular homeostasis, immune response, fibrogenesis and filament formation. These findings may help development of new therapies for skin health and aging control.PMID:34851478 | DOI:10.1007/s11033-021-06973-y

Source: Mol Biol Cell - December 1, 2021 Category: Molecular Biology Authors: Renan Paulo Martin Patricia Varela Caio Peres Gomes Maryana Mara Marins Rafael Filippelli-Silva Samira Yarak Juliana L M Soares Adriana Sanudo Jolanta Idkowiak-Baldys Siming Chen Cheng Hwang Yong Zhuang John Lyga Jo ão Bosco Pesquero Edileia Bagatin Source Type: research