Identification of Pharmacological Autophagy Regulators of Active Ulcerative Colitis

Conclusion: CASP1, SERPINA1, and CCL2 are autophagy-related hub genes of active UC. And SERPINA1 may serve as a new pharmacological autophagy regulator of UC, which provides a new target for the use of small molecules targeting autophagy in the treatment of active UC.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research