The aversive value of pain in human decision ‐making

ConclusionsThis is the first demonstration that the value of pain follows a curvilinear function and is relative to the mean and standard deviation of competing monetary rewards. These new observations significantly contribute to our understanding of how pain is assigned value when making decisions between avoiding pain and obtaining rewards.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Conclusions: Temporal trends in opioid use in cancer patients depend on patient, demographic, and tumor characteristics. Overall, understanding these correlations may help physicians better identify patient-specific risks of opioid use and could help better inform future evidence-based, cancer-specific opioid prescription guidelines.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Supportive Care Source Type: research
AbstractBackgroundThis exploratory study investigates if intra-articular injected gold microparticles in knee osteoarthritis (KOA) reduce immunomodulatory-based pain via proteomic changes in the synovial fluid (SF) and serum.MethodsThirty patients with moderate KOA were included. Intraarticular injections with 20 mg gold microparticles (72.000 particles, 20-40 µm in diameter) using the patient’s synovial fluid (SF) as carrier were performed. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) subscores for pain, stiffness, and function were assessed at inclusion, 8 weeks and 2 years The PainD...
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Medical research and development in the context of aging has, like all other medicine, been dominated for a long time by a model in which a single disease is identified by symptoms and then treated. In the context of infectious disease and inherited conditions, this is a good way to go about the matter of investigation, treatment, and assignment of resources. A patient typically has one disease at a time, and the symptoms are distinct and clearly caused by the disease in question. Indeed, the disease paradigm arose from the modern era's long road towards ever more effective control of infectious disease. The institutions a...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
University of Pittsburgh researchers studied 14 patients with chronic plantar fasciitis - which can feel 'like a nail going right through their heel' - finding belly fat could help treat them.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Condition:   Low Back Pain Interventions:   Other: Manual Lymphatic Drainage and Hot Pack;   Other: Hot Pack Sponsor:   Riphah International University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Fabry Disease Interventions:   Drug: Venglustat (GZ402671);   Drug: Placebo Sponsor:   Genzyme, a Sanofi Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Low Back Pain Intervention:   Other: ED Physical Therapy Sponsors:   Northwestern University;   Agency for Healthcare Research and Quality (AHRQ) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Maternal Care Patterns Intervention:   Other: Questionnaire Sponsor:   Rabin Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Pain Intervention:   Other: clowns Sponsor:   Central Hospital, Nancy, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Pain Interventions:   Other: Turmeric;   Other: Turmeric+Black Pepper Sponsors:   University of Alabama at Birmingham;   McCormick Science Institute Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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