Antibody dependent enhancement: Unavoidable problems in vaccine development

This article focuses on the virus-induced ADE phenomenon and its molecular mechanism. It also summarizes various attempts in vaccine research and development to eliminate the ADE phenomenon, and proposes to avoid ADE in vaccine development from the perspective of antigens and adjuvants.PMID:34656289 | PMC:PMC8438590 | DOI:10.1016/bs.ai.2021.08.003

Source: Advances in Immunology - October 17, 2021 Category: Allergy & Immunology Authors: Lele Xu Zhiqian Ma Yang Li Zhaoxia Pang Shuqi Xiao Source Type: research