Novel Likely Pathogenic Variants Identified by Panel-Based Exome Sequencing in Congenital Cataract Patients

CONCLUSION: Panel-based exome sequencing revealed three likely pathogenic variants in three unrelated Chinese families with congenital cataracts. These data expand the genetic spectrum associated with congenital cataracts.PMID:34840822 | PMC:PMC8612798 | DOI:10.1155/2021/3847409
Source: Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research

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CONCLUSION: Moderate doses of radiotherapy are curative in early-stage orbital MALT lymphoma with favorable clinical outcomes. Lower doses of radiation can reduce the toxicity further, without compromising efficacy.PMID:35027338 | DOI:10.1016/j.clml.2021.12.013
Source: Clinical Lymphoma and Myeloma - Category: Cancer & Oncology Authors: Source Type: research
J Formos Med Assoc. 2022 Jan 11:S0929-6646(21)00599-4. doi: 10.1016/j.jfma.2021.12.032. Online ahead of print.ABSTRACTPURPOSE: To assess ocular involvement in sarcoidosis and to analyze the manifestations of ocular sarcoidosis (OS) in Taiwan.METHODS: A retrospective review was performed in 364 patients diagnosed as sarcoidosis at National Taiwan University Hospital from 2015 to 2019. The OS diagnosis was based on the revised criteria of International Workshop on Ocular Sarcoidosis. Demographics, clinical manifestations, treatment and effects, complications, visual outcomes and risk factors of poor vision (
Source: J Formos Med Assoc - Category: General Medicine Authors: Source Type: research
J Cataract Refract Surg. 2022 Jan 12. doi: 10.1097/j.jcrs.0000000000000884. Online ahead of print.ABSTRACTVitreous loss is one of the adverse complications that can occur during phacoemulsification (PEA). Once vitreous loss is identified, procedural guidelines advise that PEA be ceased and the probe carefully withdrawn to minimize traction on the vitreous. The Bimanual-bipedal technique described in this paper holds the PEA probe in place and inserts the vitrectomy cutter through the pars plana port with the other hand. Following removal of vitreous around the PEA tip, the vitrectomy cutter is switched to a cutting rate of...
Source: Hand Surgery - Category: Surgery Authors: Source Type: research
CONCLUSIONS: There is a trend towards surgical subspecialisation in ophthalmology in the USA whereby some surgeons focus their surgical practice on subspecialty procedures and rarely perform surgeries in the core domain.PMID:35027354 | DOI:10.1136/bjophthalmol-2021-320295
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
AbstractThe Adolescent and Young Adult (AYA) population refers to the population of young adults and adolescents in the 15 –39 years age group. This population subgroup experiences various important life events. Head and neck malignancies are rare tumors, in general, but they are extremely rare in the AYA population. When analyzed by the primary site of the tumors, thyroid gland, soft tissue, and nasopharyngeal malig nancies are the most commonly encountered head and neck malignancies in the AYA generation. The most common histopathologic subtypes are carcinomas (thyroid carcinoma, nasopharyngeal carcinoma) and ...
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Cataract Interventions:   Drug: Dexamethasone;   Drug: Prednisolone Acetate Ophthalmic Sponsor:   EyePoint Pharmaceuticals, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To compare prostaglandin E2 (PGE-2) levels in the aqueous and pupil diameter in patients undergoing low-pulse energy femtosecond laser-assisted cataract surgery (LCS) without non-steroidal anti-inflammatory (NSAID) pretreatment with either fragmentation or capsulotomy performed first.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research
AbstractCorneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic, autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to corneal injury; however, antimicrobial agents are excluded from this present review. While practitioners may primarily rely on clinical examination techniques to assess these injuries, several pharmacological agents, such as fluorescein, lissamine green, and rose bengal, can be used to formulate a diagnosis and develop effective treatment strategies. Practitioners may choose from several analgesic medications to help with patient comfort without...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: Adopting a set of four temporary OR protocols that are often mandatory in the Western world did not reduce the POE rate. Along with previously published studies, these results challenge the necessity of these common practices which may be needlessly costly and wasteful, arguing for the reevaluation of empiric and potentially unnecessary guidelines that govern ophthalmic surgeries.PMID:35017161 | DOI:10.1136/bjophthalmol-2021-320506
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
Surg Obes Relat Dis. 2021 Dec 16:S1550-7289(21)00593-1. doi: 10.1016/j.soard.2021.12.013. Online ahead of print.NO ABSTRACTPMID:35016839 | DOI:10.1016/j.soard.2021.12.013
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Source Type: research
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