IJERPH, Vol. 18, Pages 12627: The Effect of Local and Global Interventions on Epidemic Spreading

IJERPH, Vol. 18, Pages 12627: The Effect of Local and Global Interventions on Epidemic Spreading International Journal of Environmental Research and Public Health doi: 10.3390/ijerph182312627 Authors: Jiarui Fan Haifeng Du Yang Wang Xiaochen He Epidemic spreading causes severe challenges to the global public health system, and global and local interventions are considered an effective way to contain such spreading, including school closures (local), border control (global), etc. However, there is little study on comparing the efficiency of global and local interventions on epidemic spreading. Here, we develop a new model based on the Susceptible-Exposed-Infectious-Recovered (SEIR) model with an additional compartment called “quarantine status”. We simulate various kinds of outbreaks and interventions. Firstly, we predict, consistent with previous studies, interventions reduce epidemic spreading to 16% of its normal level. Moreover, we compare the effect of global and local interventions and find that local interventions are more effective than global ones. We then study the relationships between incubation period and interventions, finding that early implementation of rigorous intervention significantly reduced the scale of the epidemic. Strikingly, we suggest a Pareto optimal in the intervention when resources were limited. Finally, we show that combining global and local interventions is the most effective way to contain the pandemi...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research