Plasmacytoid dendritic cells mediate the tolerogenic effect of CD8 < sup > + < /sup > regulatory T cells in a rat tolerant liver transplantation model

CONCLUSION: CD8+CD45RClowT cells interact with pDCs through the induction of IL-10 and TGF-β expression and are responsible for inducing immune tolerance in rat liver transplantation.PMID:34843936 | DOI:10.1016/j.trim.2021.101508

Source: Transplant Immunology - November 29, 2021 Category: Transplant Surgery Authors: Han Li Lin Zhou Ya-Nan Jia Ruo-Ling Wang Ji-Qiao Zhu Xin-Xue Zhang Wen-Li Xu Shao-Yan Liu Qiang He Xian-Liang Li Source Type: research