Case Report: Behavioral Disorder Following Hemispherotomy: A Valproate Effect?

Conclusion: We describe severe behavioral problems after hemispherotomy that subsided when valproate was tapered off. While we cannot rule out a spontaneous correction of a post-hemispherotomy network dysregulation, our report raises awareness to possible altered effects of the anticonvulsant valproic acid parallel to reorganizational processes after hemispherotomy.
Source: Frontiers in Neurology - Category: Neurology Source Type: research