Performance of 4 methods for screening of latent tuberculosis infection in patients with chronic inflammatory arthritis under TNF α inhibitors: a 24-month prospective study

CONCLUSIONS: Almost 20% of CIA patients had some evidence of LTBI, suggesting higher conversion rate after exposition to TNFi. TST was effective in identifying new cases of LTBI, but IGRAs added diagnostic power in this scenario. Our findings did not support the repetition of IGRAs after 6-Month isoniazid therapy and this approach was effective to mitigate active TB in 2 years of follow-up.PMID:34838126 | DOI:10.1186/s42358-021-00226-z
Source: Adv Data - Category: Epidemiology Authors: Source Type: research