Patterns and Predictors of Relapse in Merkel Cell Carcinoma: Results from a Population-Based Study

CONCLUSIONS: Adjuvant RT improvedRFS, withoutimpact on MCC-SS and OS. Co-morbidity rather than RT influenced OS. Adjuvant RT may be avoided instage I patients with negative SLNB and no associated high-risk factors. Prophylactic RNI could be considered in stage II with high risk features, inspite of negative SLNB. Stage III patients benefited from adjuvant RNI, but no impact on prevention of DM.PMID:34838888 | DOI:10.1016/j.radonc.2021.11.015

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 28, 2021 Category: Radiology Authors: Kurian Joseph Justina Wong Aswin Abraham Julia Zebak Anushree Patel Aoife Jones Thachuthara Umar Iqbal Truong-Minh Pham Anjali Menon Sunita Ghosh Heather Warkentin John Walker Naresh Jha Salman Faruqi Thomas G Salopek Michael Smylie Source Type: research