Excluding embryos with two novel mutations in < em > FREM2 < /em > gene by the next-generation sequencing-based single nucleotide polymorphism haplotyping

In conclusion, we first reported two novel mutations in the FREM2 gene associated with the risk of Fraser syndrome. Moreover, we described a next-generation sequencing-based single nucleotide polymorphism haplotyping method to select the 'right' embryos from patients with Fraser syndrome for in vitro fertilization and embryo transfer treatment.PMID:34837691 | DOI:10.18632/aging.203715

Source: Aging - November 27, 2021 Category: Biomedical Science Authors: Yao Zhou Xiaohui Yang Zheng Liu Yu Zhang Huaye Chen Yongfang Zhang Yuxin Hu Yanlin Ma Qi Li Source Type: research