Structural MRI-Based Measures of Accelerated Brain Aging do not Moderate the Acute Antidepressant Response in Late-Life Depression

Biological changes that accompany the aging process are seen at cellular, organ, and organismal levels and are influenced by epigenetic, genetic, and environmental factors.1 These changes affect brain processes including cognitive, motor, and sensory functions.2 “Accelerated aging” describes when biological aging occurs more rapidly than expected. Individuals with the same chronological age may exhibit different biological ages, and the difference may have clinical implications.1 Accelerated aging, assessed using biological markers such as magnetic reso nance imaging (MRI) measures, telomere length, epigenetic markers, or low-grade inflammation,3 occurs in a range of neuropsychiatric disorders, including schizophrenia, anxiety disorders, and depression.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Source Type: research

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Conclusion: Psychiatric patients in general have poorer disease control after the COVID-19 outbreak. Patients in the community appeared to be more affected than patients residing in hostels. More efforts should be directed to screening patients with pre-existing mental health disorders to enable timely interventions.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionsFindings in relation to therapy engagement, clinical benefits, participant experience and group process offer encouragement that online delivery of mindfulness for psychosis groups may be a useful addition to mental health services for people with distressing voices.
Source: Psychology and Psychotherapy: Theory, Research and Practice - Category: Psychiatry & Psychology Authors: Tags: ORIGINAL ARTICLE Source Type: research
BACKGROUND: The mental disorders included in the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 were depressive disorders, anxiety disorders, bipolar disorder, schizophrenia, autism spectrum disorders, conduct disorder, attention-de...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONCLUSIONS: PSG revealed that moderate to severe OSA was common in psychiatric patients with or without snoring. Subjective symptoms and psychotropics did not predict OSA. Therefore, PSG is needed to reveal sleep conditions in patients with psychiatric disorders.PMID:35029795 | DOI:10.1007/s11325-022-02566-6
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Source Type: research
Conclusions: Although the risk of suicide is low, psychiatric disorders, male sex, and gastric bypass procedure seem to increase the risk of suicide after bariatric surgery, indicating a role for tailored preoperative psychiatric evaluation and postoperative surveillance.
Source: Annals of Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
World Psychiatry. 2022 Feb;21(1):133-145. doi: 10.1002/wps.20941.ABSTRACTMental disorders represent a worldwide public health concern. Psychotherapies and pharmacotherapies are recommended as first line treatments. However, evidence has emerged that their efficacy may be overestimated, due to a variety of shortcomings in clinical trials (e.g., publication bias, weak control conditions such as waiting list). We performed an umbrella review of recent meta-analyses of randomized controlled trials (RCTs) of psychotherapies and pharmacotherapies for the main mental disorders in adults. We selected meta-analyses that formally as...
Source: World Psychiatry - Category: Psychiatry Authors: Source Type: research
Background Many refugee and migrant children and adolescents are in urgent need of shelter, care and protection. Greece has been a major entry point in Europe, receiving over a million refugees and migrants (37% children) since the beginning of 2015. These children and their families face a range of risks, such as violence, exploitation and abuse in their country of origin, during their journey, and on arrival. It is estimated that 22% of individuals living in displacement experience a mental disorder such as depression, anxiety, post-traumatic stress disorder, bipolar disorder or schizophrenia.1 Promising examples of comm...
Source: British Journal of Sports Medicine - Category: Sports Medicine Authors: Tags: BJSM Service spotlight Source Type: research
CONCLUSIONS: Psychopathology, particularly positive symptoms, was associated with gaze avoidance and pupil diameter in patients with schizophrenia. Evaluating the characteristics of eye movements in patients with schizophrenia will enable better understanding of their symptoms.PMID:34974374 | DOI:10.1016/j.ajp.2021.102974
Source: Asian Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
Yale J Biol Med. 2021 Dec 29;94(4):623-635. eCollection 2021 Dec.ABSTRACTWilliams Syndrome (WS) is a rare genetic multisystem disorder that occurs because of a deletion of approximately 25 genes in the 7q11.23 chromosome region. This causes dysmorphic facial appearances, multiple congenital cardiovascular defects, delayed motor skills, and abnormalities in connective tissues and the endocrine system. The patients are mostly diagnosed with mild to moderate mental retardation, however, they have a hyper sociable, socially dis-inhibited, and outgoing personality, empathetic behavior, and are highly talkative. Oxytocin (OT), a...
Source: The Yale Journal of Biology and Medicine - Category: Universities & Medical Training Authors: Source Type: research
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