Selenium alleviates mercury chloride-induced liver injury by regulating mitochondrial dynamics to inhibit the crosstalk between energy metabolism disorder and NF- κB/NLRP3 inflammasome-mediated inflammation
In conclusion, our results suggested that Se inhibited energy metabolism disorder and inflammation by regulating mitochondrial dynamics, thereby alleviating HgCl2-induced liver injury in chickens. These results are expected to provide potential intervention and therapeutic targets for diseases caused by inorganic mercury poisoning.PMID:34837874 | DOI:10.1016/j.ecoenv.2021.113018
Source: Ecotoxicology and Environmental Safety - Category: Environmental Health Authors: Pei-Chao Gao Jia-Hong Chu Xue-Wei Chen Lan-Xin Li Rui-Feng Fan Source Type: research
More News: Chloride | Environmental Health | Genetics | Liver | Mitochondrial Disease | Poisoning | Selenium | Study | Urology & Nephrology