Genes, Vol. 12, Pages 1916: The Decisive Case-Control Study Elaborates the Null Association between ADAMTS5 rs226794 and Osteoarthritis in Asians: A Case-Control Study and Meta-Analysis
Conclusions: This study indicates that the gene polymorphism, ADAMTS5 rs226794, is not significantly associated with knee osteoarthritis. Additionally, assuming that the cumulative sample size in the allele model is sufficient, we confirmed that the G allele is not a risk factor for osteoarthritis. This study integrated all available evidence to arrive at this conclusion, and it suggests that no additional studies are necessary.
Source: Genes - Category: Genetics & Stem Cells Authors: Chung-Cheng Kao Hsiang-En Hsu Yi-Chou Chen Ming-Yu Tu Su-Wen Chuang Sui-Lung Su Tags: Article Source Type: research