A study of the healthcare resource use for the management of postpartum haemorrhage in France, Italy, the Netherlands, and the UK

Every day, almost 200 women worldwide die from bleeding complications after childbirth, known as postpartum haemorrhage (PPH) [1]. Uterine atony (insufficient uterine contraction after delivery of the placenta) is the primary cause of 58-90% of PPH cases [2 –4]. Rates of PPH are increasing in many developed countries due to increasing rates of uterine atony [5–8].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Source Type: research

Related Links:

Purpose of review The aim of this study was to summarize available evidence regarding the safety and efficacy of intravenous thrombolysis (IVT) using recombinant tissue-plasminogen activator (rt-PA) in acute ischemic stroke (AIS) patients with specific comorbidities and potential contraindications to systemic reperfusion therapy. Recent advances in IVT implementation in wake-up stroke and in extended time window using advanced neuroimaging will also be highlighted. Recent findings Despite theoretical concerns of a higher bleeding risk with IVT, there are no data showing increased risk of symptomatic intracerebra...
Source: Current Opinion in Neurology - Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Diana Aguiar de Sousa Source Type: research
Conditions:   Risk Factors;   Complication of Surgical Procedure;   Complication of Treatment;   Complication of Anesthesia;   Long Term Effects After Emergency Surgery;   Long Term Effects After GI Bleeding Intervention:   Other: Observational study of different treatments and time to treatment Sponsors:   Region Skane;   Lund University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractPurpose of ReviewMultiple guidelines and recommendations have been written to address the perioperative management of antiplatelet and anticoagulant drugs. In this review, we evaluated the recent guidelines in non-cardiac, cardiac, and regional anesthesia. Furthermore, we focused on unresolved problems and novel approaches for optimized perioperative management.Recent FindingsVitamin K antagonists should be stopped 3 to 5 days before surgery. Preoperative laboratory testing is recommended. Bridging therapy does not decrease the perioperative thromboembolic risk and might increase perioperative bleeding risk. In pat...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
Acute gastrointestinal bleeding is a potentially life-threatening condition that requires rapid intervention. In critically ill patients who are refractory to other therapies, balloon tamponade devices can be lifesaving.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Techniques and Procedures Source Type: research
ConclusionMost of the post-extraction bleedings were grade 1, which can be stopped by eligibly pressing gauze by surgeons. If patients taking anticoagulants are scheduled to undergo multiple teeth extractions or their HAS-BLED score are above 3 points (if warfarin), we recommend informing patients risk of post-extraction bleeding before operation, taking carefully hemostasis, and instructing patients to bite down accurately on the gauze for longer than usual.
Source: Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Dr. Kalen N. Wright: Today's case is that of a 46-year-old woman who presented to the emergency department (ED) for evaluation of a surgical site infection (SSI). She reported that 1 month prior she underwent abdominoplasty, liposuction, and bilateral buttock augmentation at a plastic surgery clinic located in the Dominican Republic (DR). Medical records from the clinic were not available and so the history was obtained from the patient's recollection of events. She reported clinic re-evaluation 3 days postoperatively for surgical site bleeding and was diagnosed with anemia.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Case Presentations of the Harvard Affiliated Emergency Medicine Residencies Source Type: research
ConclusionsOur simulation platform for thrombolysis with well-tuned model parameters can be used to evaluate and optimise treatment regimens of existing and new thrombolytic therapies via benefit/risk assessment under various therapeutic scenarios.
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
by Yu-Wen Chien, Hui-Ning Chuang, Yu-Ping Wang, Guey Chuen Perng, Chia-Yu Chi, Hsin-I Shih Dengue patients have an increased risk of acute gastrointestinal (GI) bleeding. However, whether dengue virus (DENV) infection can cause an increased long-term risk of GI bleeding remains unknown, especially among elderly individuals who commonly take antithrombotic drugs. A retrospective populati on-based cohort study was conducted by analyzing the National Health Insurance Research Databases. Laboratory-confirmed dengue patients from 2002 to 2012 and four matched nondengue controls were identified. Multivariate Cox proportional ha...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
This study aimed to compare the operative and clinical outcomes and survival between EPP and P/D.MethodsWe performed a retrospective analysis of the surgical and clinical data of 40 patients who underwent either EPP (n = 18) or P/D (n = 22) for MPM at our institution between January 2000 and December 2018.ResultsIn comparison to EPP, P/D was associated with a higher intraoperative bleeding volume (1175 vs 1805  ml,p  =  0.0020) and greater duration of postoperative thoracic drainage (3 vs 16 days,p 
Source: Surgery Today - Category: Surgery Source Type: research
Hermansky-Pudlak syndrome (HPS), a rare heterogeneous autosomal recessive disorder, is characterized by oculocutaneous albinism (OCA) and a bleeding diathesis due to a defect regarding melanosomes and platelet delta (δ)-granule secretion. Interestingly, patients with HPS type 2 (HPS-2) or HPS type 10 (HPS-10) present additionally with an immunological defect. We investigated three patients (IP1, IP2, and IP3) who suffer from a bleeding diathesis. Platelet aggregometry showed impaired platelet function and flow cytometry revealed a severely reduced platelet CD63 expression hinting to either a defect of platelet delta ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
More News: Biology | Bleeding | France Health | Georgia Health | Italy Health | Netherlands Health | OBGYN | Study | Women