Cardioprotective effects of Amiodarone in a rat model of epilepsy-induced cardiac dysfunction

CONCLUSION: Amiodarone pre-treatment prevented the anticipated cardiac injury induced during epilepsy. Amiodarone possessed an anti-convulsive potential, protected the cardiac muscle and preserved its histological architecture. Therefore, amiodarone could be recommended as a protective therapy against cardiac dysfunction during epileptic seizures with favorable effect on seizure activity.PMID:34796981 | DOI:10.1111/1440-1681.13615
Source: Clinical and Experimental Pharmacology and Physiology - Category: Drugs & Pharmacology Authors: Source Type: research