Understanding Cu(II)-based systems for C(sp3) –H bond functionalization: insights on the synthesis of aza-heterocycles

Org. Biomol. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1OB02118D, PaperMarc Camats, Isabelle Favier, Sonia Ladeira, Daniel Pla, Montserrat Gomez Herein we report the synthesis of imidazo[1,5-a]pyridine heterocycles via a Cu(II)-mediated functionalization of α’-C(sp3)–H bonds of pyridinylaldimines and subsequent cyclization. This strategy exploits the inherent directing ability of heteroleptic aldimine... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research