Primary Idiopathic Cutaneous Intestinal Metaplasia: First Case

In this study, we described a unique case of cutaneous metaplasia on the elbow of a 25-year-old man who had a clinical history of epidermolysis bullosa simplex, but had no history of any gastrointestinal disease. The lesion had been clinically stable for 5 years. Histopathologically, the epithelium showed many columnar cells with mucinous cytoplasm, with no atypia or mitoses. The proliferation rate was low (7% by Ki67). The metaplastic areas expressed epithelial membrane antigen, carcinoembryonic antigen, cytokeratin 7, MUC5AC, MUC2, and Cyclin-D1.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research

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ConclusionsThe risk of perioperative thrombosis in UC patients was considered similar to that in CRC, so active thromboprophylaxis should be administered to UC patients while paying attention to bleeding.Trial registrationThis study was registered with the Japanese Clinical Trials Registry as UMIN000042004 (http://www.umin.ac.jp/ctr/index.htm).
Source: Surgery Today - Category: Surgery Source Type: research
The articles appeared in the Journal of Crohn's and Colitis, the official journal of the European Crohn's and Colitis Organisation (ECCO) and date back to 2007.Undark
Source: Medscape Gastroenterology Headlines - Category: Gastroenterology Tags: Gastroenterology News Source Type: news
Women with inflammatory bowel disease often worry about their reproductive health and they expect their gastroenterologist to initiate this conversation, according to a new qualitative study.Reuters Health Information
Source: Medscape Gastroenterology Headlines - Category: Gastroenterology Tags: Gastroenterology News Source Type: news
Conditions:   Inflammatory Bowel Diseases;   Depressive Episode;   Recurrent Depressive Disorder;   Anxiety Disorder;   Psychological Disorder;   Self Harm;   Suicide, Attempted;   Parasuicide;   Eating Disorders;   Body Image Disorder;   Attention Deficit Hyperactivity Disorder;   B ehavioral Disorder;   Adjustment Disorders;   Acute Stress Disorder;   Schizophrenia;   Bipolar Disorder;   Post-traumatic Stress Disorder;   Sle...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Ulcerative Colitis;   Efficacy, Self;   Biologics;   Mesalazine Interventions:   Drug: Infliximab;   Drug: Vedolizumab;   Drug: Mesalazine Sponsor:   Sixth Affiliated Hospital, Sun Yat-sen University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Inflammatory Bowel Diseases;   Depressive Episode;   Recurrent Depressive Disorder;   Anxiety Disorder;   Psychological Disorder;   Self Harm;   Suicide, Attempted;   Parasuicide;   Eating Disorders;   Body Image Disorder;   Attention Deficit Hyperactivity Disorder;   B ehavioral Disorder;   Adjustment Disorders;   Acute Stress Disorder;   Schizophrenia;   Bipolar Disorder;   Post-traumatic Stress Disorder;   Sle...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Ulcerative Colitis;   Efficacy, Self;   Biologics;   Mesalazine Interventions:   Drug: Infliximab;   Drug: Vedolizumab;   Drug: Mesalazine Sponsor:   Sixth Affiliated Hospital, Sun Yat-sen University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: The Norwegian version of MFI-20 is valid, reliable and responsive. The instrument can safely be used in studies using fatigue as an endpoint.PMID:35076321 | DOI:10.1080/00365521.2022.2029939
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Evid Based Complement Alternat Med. 2022 Jan 15;2022:8528938. doi: 10.1155/2022/8528938. eCollection 2022.ABSTRACTInflammatory bowel disease (IBD) is a chronic inflammatory disease with a high prevalence and canceration rate. The immune disorder is one of the recognized mechanisms. Acupuncture is widely used to treat patients with IBD. In recent years, an increasing number of studies have proven the effectiveness of acupuncture in the treatment of IBD, and some progress has been made in the mechanism. In this paper, we reviewed the studies related to acupuncture for IBD and focused on the immunomodulatory mechanism. We fou...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Source Type: research
Trends Mol Med. 2022 Jan 21:S1471-4914(21)00323-3. doi: 10.1016/j.molmed.2021.12.006. Online ahead of print.ABSTRACTBile acids are potent signaling molecules exerting diverse actions through bile acid-activated receptors. Among them, the Farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 (TGR5; GPBAR1), modulate the inflammation occurring in chronic/acute hepatitis, cholestasis, and inflammatory bowel disease. A role for other bile acid-responsive receptors in this context is emerging. This review aims to summarize recent advances on the immune-modulatory actions of the bile acid-responsive receptors Sh...
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
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