Peculiar Histopathologic Feature of an Erythematous/Morbilliform Eruption in a COVID-19–Positive Patient

We present the case of a COVID-19–positive woman with a morbilliform rash, whose skin biopsy showed the presence of some peculiar cytopathic epidermal changes that could represent a possible distinctive histopathological feature related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection The presence of viral particles in the keratinocytes with additional positivity of endothelial cells and eccrine glands by immunohistochemistry using an anti-SARS‐CoV‐2 Spike S1 antibodies supports a causal relation of the lesions with SARS‐CoV‐2 infection.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research