Construct Validity and Item Response Theory Analysis of the PROMIS-29 v2.0 in Recipients of Lumbar Spine Surgery

Conclusion. The PROMIS-29 v2.0 measures several different constructs pertinent to a patient's health and recovery during spine surgery. We feel that the PROMIS-29 v2.0 tool is a useful and effective outcome measure for populations who receive spine surgery. Level of Evidence: 4
Source: Spine - Category: Orthopaedics Tags: HEALTH SERVICES RESEARCH Source Type: research

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ConclusionIndividualised physiotherapy for low back pain appears to work predominately by facilitating an early reduction in disability, which in turn leads to improvements in other biopsychosocial outcomes. The current study cannot rule out that unmeasured mechanisms (such as tissue healing or reduced inflammation) may mediate the relationship between individualised physiotherapy treatment and improvement in disability. Further data-driven analyses involving a broad range of plausible biopsychosocial variables are recommended to fully understand how treatments work for people with low back pain. Trials registrationACTRN12609000834257.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research
CONCLUSIONS: SCS may improve the HRQoL and functionality of FBSS patients with refractory pain in the long-term compared to CMM alone.PMID:34554696
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
Disrupted and deprived sleep —known to increase the risk of psychiatric symptoms such as depression and anxiety and other health problems—is a common experience lived by inmates in U.S. jails and prisons. Apaper inPsychiatric Services in Advance describes lawsuits by inmates that have attempted to address this problem and discusses clinicians ’ responsibility to evaluate and treat inmates for sleep-related problems.APA past President Ren ée L. Binder, M.D., Nathaniel Morris, M.D., and Jessica Holliday, M.D., M.P.H., of the University of California, San Francisco, outlined five conditions that have ...
Source: Psychiatr News - Category: Psychiatry Tags: correctional systems incarcerated jail prison psychiatric disorders Psychiatric Services in Advance Renee Binder sleep sleep deprivation Source Type: research
SPRING HOUSE, PENNSYLVANIA, June 2, 2021 – Today the Janssen Pharmaceutical Companies of Johnson &Johnson announced new efficacy and safety data for first-in-class TREMFYA® (guselkumab), including data from the first study evaluating a selective IL-23 inhibitor in adult patients with active PsA, all of whom had demonstrated inadequate response or intolerance to TNFi.1 In the COSMOS Phase 3b study, significantly higher proportions of patients treated with TREMFYA showed joint symptom improvement and complete skin clearance versus placebo at week 24 in this true TNFi-IRa patient population, which is often more ...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
When Ghenya Grondin starts rattling off the symptoms she still experiences a year after getting sick with what she believes was COVID-19, she has to pause to consult a list she keeps on her phone for occasions like this one. Exhaustion. Fevers. Headaches. Body aches. Chest pain and shortness of breath. Nausea and gastrointestinal problems. Dry eyes. Brain fog and memory loss—hence her need for a digital list, which goes on and on. While Grondin’s physical symptoms are bad enough to keep her mostly homebound and unable to do her work as a postpartum doula, the constant mental fogginess has hit her hard emotional...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation.PMID:33607619 | DOI:10.3171/2020.8.SPINE191551
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Source Type: research
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation. PMID: 33607619 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Tags: J Neurosurg Spine Source Type: research
Shortly after the end of WWII, a British medical officer inspecting a military hospital in Germany observed a treatment for pressure injuries developed by Nazi doctors.  The officer’s name was Captain James Fulton Neil and his case report was published in the British Medical Journal along with a photograph of the unfortunate patient reproduced above.  The treatment employed suspension by wires drilled into pelvic bones, and I discovered Captain Neil’s article while researching the history of wound care. This post is a summary of my paper recently published in Advances in Skin &Wound Care that desc...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - Category: Geriatrics Authors: Tags: Featured Medical Articles Geriatric Medicine Pressure Injuries & Wound Care bedsore bedsores decubiti decubitus ulcer Jeff Levine MD Jeffrey M Levine MD medical history pressure sore pressure sores pressure ulcer pressure ulcers Source Type: blogs
ConclusionConclusion: CFT did not improve the majority of the hypothesized mediators (stress, fear of physical activity, coping, depression, anxiety and sleep) and these mediators were not associated with either disability or pain. Unfortunately, the proportion of missing data in this study is substantial and these findings can only be considered hypothesis ‐generating. Therefore, future research should examine replicating the results of this study to verify the role of self‐efficacy and other proposed mediators (e.g. stress, coping, sleep, fear) on clinical outcomes.Significance An exploration of seven potential med...
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
In this study, causal mediation analysis was used to determine whether the effect of CFT on disability and the lack of effect on pain (relative to a group exercise and educati on intervention) is mediated by certain psychological and lifestyle factors. Hypothesised mediators measured were pain self‐efficacy, stress, fear of physical activity, coping, depression, anxiety, and sleep, at 6 months. The outcomes measured were functional disability and pain intensity at 12 mo nths. This causal mediation study shows that the majority of benefit of CFT (relative to a group exercise and education intervention) for disability is d...
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
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