Clinical Effect of Systemic Steroids in Patients with Cirrhosis and Septic Shock

Conclusion: The use of systemic steroids was more prevalent in cirrhotic patients with higher vasopressor requirements. It was not associated with decreased mortality or increased ICU- and hospital-free days, or to adverse effects.
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research

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ConclusionsICH in COV19  + patients has distinct NCCT imaging features and a higher speed of bleeding. This association is not mediated by antithrombotic therapy and deserves further research to characterize the underlying biological mechanisms.
Source: Neuroradiology - Category: Radiology Source Type: research
Pediatr Res. 2022 Jan 14. doi: 10.1038/s41390-021-01873-0. Online ahead of print.ABSTRACTMultisystem inflammatory syndrome in children (MIS-C) is a hyperinflammatory response observed in children several weeks to months after acute infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). On review of all published cases of thromboembolism (TE) as a complication of MIS-C, 33 cases of TE were found with incidence ranging from 1.4 to 6.5%. TE occurred mostly in children aged 12 years and above. One-third of the cases were cerebral infarcts and the remaining cases included intracardiac and radial arterial t...
Source: Pediatric Research - Category: Pediatrics Authors: Source Type: research
In conclusion, neurovascular imaging in Loeys Dietz syndrome type III patients revealed abnormalities such as aneurysm, tortuosity, coiling and kinking in the vast majority of patients, but clinical events were rare. Neurovascular screening and follow up is advised in all Loeys Dietz syndrome type III patients.PMID:35031499 | DOI:10.1016/j.ejmg.2022.104424
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Ann Surg Oncol. 2022 Jan 15. doi: 10.1245/s10434-021-11154-z. Online ahead of print.ABSTRACTINTRODUCTION: Delayed gastric emptying (DGE) is a common complication in surgery, but incidence and relevance following multivisceral resection are unknown.METHODS: Data from 100 consecutive patients treated for primary retroperitoneal sarcoma (RPS) were analyzed from our institutional prospectively maintained database from January 2019 to April 2020. DGE severity was graded according to the International Study Group of Pancreatic Surgery and classified as primary or secondary to other complications. The primary outcome was incidenc...
Source: Ann Oncol - Category: Cancer & Oncology Authors: Source Type: research
In conclusion, the treatment responses of immunotherapy, either alone or in combination with other therapies, were highly variable in patients with ATC and should be carefully monitored along with the side effects.PMID:35031200 | DOI:10.1016/j.jfma.2022.01.003
Source: J Formos Med Assoc - Category: General Medicine Authors: Source Type: research
Biomed Pharmacother. 2022 Jan 12;147:112623. doi: 10.1016/j.biopha.2022.112623. Online ahead of print.ABSTRACTBACKGROUND: A better understanding of the evolution of cirrhosis after hepatitis C virus (HCV) clearance is essential since the reversal of liver injury may not happen. We aimed to assess the evolution of plasma metabolites after direct-acting antivirals (DAAs) therapy and their association with liver disease scores in HIV/HCV-coinfected patients with advanced HCV-related cirrhosis.METHODS: We performed a prospective study in 49 cirrhotic patients who started DAAs therapy. Data and samples were collected at baselin...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Source Type: research
CONCLUSIONS PMD has appreciable clinical value for predicting the mortality of patients with TIPS implantation. In addition, PMD is superior to established scoring systems for identifying high-risk patients with a poor prognosis.PMID:35031594 | DOI:10.12659/MSM.934057
Source: Medical Science Monitor - Category: Research Authors: Source Type: research
J Emerg Med. 2022 Jan 12:S0736-4679(21)00748-4. doi: 10.1016/j.jemermed.2021.10.009. Online ahead of print.ABSTRACTBACKGROUND: Hemorrhagic cholecystitis is a rare cause of abdominal pain. Most often described in the setting of blunt abdominal trauma, anticoagulation use, coagulopathy (such as cirrhosis or renal failure), and malignancy (biliary angiosarcoma), this rare condition can be difficult to identify unless high on the differential. With point-of-care ultrasound becoming more commonplace in the emergency department (ED), this tool can be successfully used to make a timely diagnosis in the correct clinical context.CA...
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
CONCLUSION Toxic megacolon should be considered in a patient with Campylobacter colitis who becomes critically unwell. Despite treatment, toxic megacolon is associated with significant risk of mortality.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSION: AEA use was associated with increased survival of cirrhotic patients who developed bacteremia. Strategies for AEA use, tailored according to the local epidemiological patterns, are needed to improve survival of cirrhotic patients with bacteremia. PMID: 25834324 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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