An overview of heart rhythm disorders and management in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is the commonest adult form of muscular dystrophy, presenting with a constellation of systemic findings secondary to a CTG triplet expansion of the non-coding region of the DMPK gene. Cardiac involvement is frequent, with conduction disease, supraventricular and ventricular arrhythmias being the most prevalent cardiac manifestations, often developing from a young age. The development of cardiac arrhythmias has been linked to increased morbidity and mortality, with sudden cardiac death well described.

Source: Heart Rhythm - November 25, 2021 Category: Cardiology Authors: Thomas D. Gossios, Rui Providencia, Antonio Creta, Oliver R. Segal, Nikoletta Nikolenko, Chris Turner, Luis R. Lopes, Karim Wahbi, Konstantinos Savvatis Source Type: research