Cinnamoyl amide type chiral P,olefin ligands for Pd-catalyzed reactions

Org. Biomol. Chem., 2021, Advance Article DOI: 10.1039/D1OB02086B, PaperTakashi Mino, Yohei Fujisawa, Shizuki Yoshida, Mitsuru Hirama, Takumu Akiyama, Ryo Saito, Yasushi Yoshida, Yoshio Kasashima, Masami Sakamoto We have synthesized cinnamoyl amide type chiral P,olefin ligand and obtained separable diastereomers of4d and demonstrated Pd-catalyzed asymmetric allylic substitution reactions of indoles using this chiral ligand with high enantioselectivities (up to 98% ee). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research